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The duration of the febrile period is about 10 days. Further, symptoms of Baclofen pills syndrome manifest: bleeding of the gums increases, nosebleeds, hematuria, and melena are noted. Blood pressure drops to 60 mm Hg. Art., with massive bleeding develops hemorrhagic shock. Perhaps the appearance of symptoms of CNS damage with an increase in neurological deficit (excitation, stupor, signs of encephalitis). The recovery period ranges from 2 weeks to several months.

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Treatment should be carried out in isolation of the patient under the supervision of an infectious disease specialist. When complications are attached, consultation of specialized specialists (neurologist, pulmonologist, nephrologist, cardiologist) may be required. Strict bed rest is required. The main method of therapy is the transfusion of convalescent plasma. This method gives the best results at the initial stages of the disease (up to 8 days).

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There are reports of positive results of treatment with ribavirin. This method is especially relevant in the absence of immune plasma. According to WHO recommendations, the drug is administered intravenously on the first day at a dose of 30 mg/kg once, then 15 mg/kg 4 times a day. 4 days and 7.5 mg/kg/day.

In parallel, symptomatic treatment is carried out with the correction of developed disorders (detoxification therapy, compensationblood volume reduction, the use of cardiovascular drugs, antipyretic drugs, correction of hemostasis disorders).

With a timely recognized disease and proper treatment, the prognosis is favorable. In the case of the development of severe forms, the duration of the Argentine hemorrhagic fever is about 11 days, and the mortality rate reaches 15%. Non-specific prevention measures include the fight against rodents in endemic areas through the use of poisonous substances and special traps.

In addition, it is necessary to use respirators in dusty work. Vaccination of local residents allows you to control the course of the disease. To date, a live attenuated vaccine is used, experimental samples are being tested. The use of ribavirin as emergency prophylaxis is not recommended. The exception is pregnant patients who have been in contact with the patient.

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Argentine hemorrhagic fever is an acute viral disease related to zoonoses with natural focality. It is characterized by fever, exanthema, various severity of thrombohemorrhagic syndrome.

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